The TMA Core at Johns Hopkins is a University Service Center/Shared Resource that is part of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins and the Department of Pathology .

The TMA Core has constructed 566 TMAs for 43 investigators containing ~96,000 tissue cores from tumors from the prostate, breast, pancreas, gall bladder, cervix, ovary, brain, liver, urinary bladder, salivary glands, esophagus, head and neck, thyroid and various cell lines. Users have published at least 118 manuscripts involving JHU TMAs.

Instrumentation is available to automatically capture high resolution digital images of TMA spots and perform semi-automated quantitative image analysis. Users have access to a set of Open Source web-based software tools and backend database (TMAJ) that were developed to facilitate the all facets of research involving TMA technology from TMA design, data entry, image diagnosis, analysis, and publishing on the Internet. Recently we have incorporated comprehensive histology services into the TMA core by moving the Oncology Histology Lab into the TMA lab space. Also, we have incorporated immunohistochemistry and fluorescence in situ hybridization services into the TMA Core.