 |
 | ||||||
 |
 |
 |
 |
 |
 | ||
 |
 |
 |
 |
 |
 |
 | |
 | |||||||
 |
About Tissue Microarrays Tissue Microarrays (TMAs) consist of paraffin blocks where up to 1000 individual tissue cores have been inserted in an arrayed fashion (1). These miniaturized collections of tissue spots result in a dramatic increase in throughput for in situ examination of gene status and gene expression from archival specimens. All available methods for examination of histological sections, including immunohistochemistry, in situ hybridization, DNA ploidy analysis, nuclear morphometry, and fluorescent in situ hybridization can be performed on sections from TMA blocks. Many clinical specimens contain limited tissues for study. TMAs can expand the number of studies that can be performed from these extremely valuable specimens. TMAs have been validated as useful tools for the evaluation of various biomarkers, especially in oncology patients.
|
|
© Copyright 2003 | All Rights Reserved | |